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Randomized controlled trial compares erectile dysfunction incidence in patients undergoing urethroplasty, highlighting the impact of surgical management.
Background: Bulbar urethral stricture is a common urological condition, and its surgical management may impact erectile function. The relative effect of end-to-end anastomosis (EEA) versus oral mucosa graft (OMG) urethroplasty on postoperative erectile function remains uncertain. Objective: To compare the incidence of erectile dysfunction (ED) following EEA versus OMG urethroplasty in adult males with bulbar urethral stricture. Methods: tricture were randomized to undergo either EEA or OMG urethroplasty. Erectile function was assessed preoperatively and postoperatively at 3, 6, and 12 months using the International Index of Erectile Function-5 (IIEF-5). The primary outcome was the occurrence of ED at 12 months. Secondary outcomes included stricture recurrence and complications. Results: EEA at all follow-up points. The incidence of ED at 12 months was higher in the EEA group compared to the OMG group. Conclusion: G are effective for stricture repair, but OMG is associated with better erectile function preservation
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Singh et al. (2025) studied this question.
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