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This research explores the progress and challenges in cell therapy for type 1 diabetes.

October 1, 2025Cell TransplantationOpen Access

Cell therapy for type 1 diabetes: Tracing historical progress and exploring emerging technologies

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This research explores the progress and challenges in cell therapy for type 1 diabetes.
Review of historical advancements in cell therapy
Analysis of emerging technologies like stem cell-derived islet clusters and gene editing
Consideration of regulatory and logistical challenges
Cell therapy shows promise for insulin independence and glycemic control
Challenges include cell delivery, engraftment, and long-term functionality
Patient-centered approaches are essential for successful therapies.

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Cell therapy improves glycemic control in type 1 diabetes, indicating new approaches may enhance patient outcomes.

Perrier et al. (2025) studied this question.

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