Unveiling the best: A comparative analysis of three grafted materials for root coverage – A randomized controlled clinical trial

Introduction: Subepithelial connective tissue grafts (CTGs) represent the gold standard of treatment for gingival recession; however, the method is associated with some limitations, stemming from necessity of a donor site and the inherent complexity of the harvesting technique. The present study utilizes Mucoderm ® (porcine-derived collagen matrix) and amnion membrane (allograft), as a substitute approach for root coverage. Objectives: The purpose of the study is to evaluate the efficaciousness of the root coverage outcomes when employing Mucoderm ® and amniotic membrane (AM) versus CTG. Materials and Method: A randomized clinical trial was conducted comparing coronally advanced flap with Mucoderm ® , AM and CTG was conducted involving 15 patients subdivided into groups of five. The periodontal pocket depth, clinical attachment level, recession depth, and keratinized tissue width were measured preoperatively and at 1 and 3 months postoperatively. Results: Statistical analysis showed that Mucoderm ® showed statistically significant results compared to CTG with regard to clinical parameters and complete coverage, whereas AM showed poorer results in terms of thickness of the gingiva. Conclusion: The study results indicated that Mucoderm® and AM could serve as viable alternatives CTGs in root coverage procedures.