Fast Metal-free CO2-Mediated N-Aryl Amide Synthesis from Nitroarenes under Continuous Flow Conditions.

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CO2-mediated synthesis produces functionalized N-aryl amides from nitroarenes, suggesting a novel approach to organic synthesis.

Functionalized N-aryl amides synthesized efficiently under continuous flow conditions.
This approach improves access to diverse compounds, enhancing organic synthesis.
Continuous flow method utilized for direct amidation of nitroarenes, increasing reaction efficiency.
Highlights a promising strategy in organic synthesis without the use of metals.

Geraldo et al. (2025) studied this question.

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