Development and optimization of green extraction of naringin in Citrus grandis ‘Tomentosa’ using natural deep eutectic solvents (NADES) and investigation of lung cancer therapeutics mechanisms

January 1, 2025RSC AdvancesOpen Access

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Key Points

To develop and optimize a green extraction method for naringin using natural deep eutectic solvents and investigate its mechanisms against lung cancer.
Utilized natural deep eutectic solvents for the extraction of naringin from Citrus grandis
Analyzed the extracted naringin for its anti-cancer properties
Investigated the therapeutic mechanisms of naringin in lung cancer models
Successfully optimized the extraction method for naringin
Demonstrated anti-cancer effects of naringin on lung cancer cells
Identified potential therapeutic mechanisms of naringin in cancer treatment

This research demonstrates an extraction method for naringin from citrus, revealing potential therapeutics for lung cancer.

A novel green extraction method of naringin and its anti-lung cancer mechanism of Citrus grandis ‘Tomentosa’.

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Yang et al. (2025) studied this question.

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