Review highlights the role of transcription factors and metabolic pathways in abdominal fat deposition in chickens, suggesting implications for breeding programmes.
Abdominal fat deposition in chickens is an important trait that affects meat quality, reproductive performance and overall production efficiency. This review analyses key aspects of the genetic regulation of this process, including the role of transcription factors, microRNAs and key metabolic pathways. The prospects for applying knowledge of molecular mechanisms in breeding programmes to achieve an optimal balance between production performance, product quality and reduced feed costs are discussed. Detailed attention is given to genetic studies, including GWAS, transcriptomics and the use of genome editing technologies, which reveal the polygenic nature of fat deposition. Mechanisms regulating lipogenesis and adipocyte differentiation are described, as well as interactions between signalling pathways such as PPAR and SREBP. The findings emphasise the importance of molecular approaches to improve the environmental sustainability of the industry and meet consumer demands for high quality meat products.
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A.P. Dysin (2025) studied this question.
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