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January 1, 2025Генетика / Russian Journal of Genetics

The human genome and COVID-19

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Authors

VSV. A. Stepanov

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Overview

Genome-wide association studies uncover genetics linked to COVID-19 severity, suggesting new diagnostic and therapeutic pathways.

Key Points

  • This research examines the influence of host genetics on COVID-19 susceptibility and severity.
  • Genome-wide association studies of COVID-19 patients
  • Analysis of whole-genome and whole-exome data
  • Study of genomic regions associated with infection risk and disease severity
  • Evaluation of post-genomic mechanisms like gene expression and methylation
  • Identified significant genomic regions linked to COVID-19 susceptibility
  • Revealed patterns of gene expression and methylation in response to the virus
  • Highlighted potential for targeted treatment and prevention strategies for COVID-19

Cite This Study

V. A. Stepanov (2025) studied this question.

synapsesocial.com/papers/69255737c0ce034ddc35ad51https://doi.org/10.7868/s3034510325050012
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  4. 4SARS-CoV-2 disrupts host gene networks: unveiling key hub genes as potential therapeutic targets for COVID-19 management2024
  5. 5A modern view on the role of single nucleotide polymorphism of human genes in the formation of unfavorable consequences of the new coronavirus disease (COVID-19)2024