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January 1, 2025Food & FunctionOpen Access

Expression of concern: An in vitro screening method for probiotics with antidepressant-like effect using the enterochromaffin cell model

Peijun Tian Huiyue Zhu Renying Zou Qin‐ming Kong Mengshu Xu Jianxin Zhao Hao Zhang Wei Chen Gang Wang

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Key Points

To develop a screening method to evaluate probiotics for potential antidepressant-like effects using a cell model.
Developed an in vitro screening method
Utilized enterochromaffin cell model
Assessed effects of various probiotics
Identified specific probiotics demonstrating antidepressant-like effects
Showed potential for probiotics to influence enterochromaffin cell activity

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Implication

In vitro screening method identifies probiotics with antidepressant-like effects in enterochromaffin cells, suggesting new treatment avenues.

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Cite This Study

Tian et al. (2025) studied this question.

synapsesocial.com/papers/69255737c0ce034ddc35b003 https://doi.org/10.1039/d5fo90104a

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Keep reading

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1An <i>in vitro</i> screening method for probiotics with antidepressant-like effect using the enterochromaffin cell modelOriginal Research · 2026
2Expression of concern: Ingestion of <i>Bifidobacterium longum</i> subspecies <i>infantis</i> strain CCFM687 regulated emotional behavior and the central BDNF pathway in chronic stress-induced depressive mice through reshaping the gut microbiota2025
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5Ingestion of <i>Bifidobacterium longum</i> subspecies <i>infantis</i> strain CCFM687 regulated emotional behavior and the central BDNF pathway in chronic stress-induced depressive mice through reshaping the gut microbiotaOriginal Research · 2026

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