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This research demonstrates synthesis of a new nitrogen macroheterocycle, suggesting potential applications in drug development.
A method for the synthesis of a new 18-membered nitrogen macroheterocycle was developed. It was based on the acid-catalytic cyclocondensation of 1-[(2E,Z)-2-hydrazono-2-phenylethyl]-5-methyl-1H-pyrazole-3-carbohydrazide, a reaction product of methyl 5-methyl-1-(2-oxo-2-phenylethyl)-1H-pyrazole-3-carboxylate with hydrazine.
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A. O. Kharaneko (2025) studied this question.
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