Analysis reveals cognitive impairment may relate to choroid plexus alterations in Alzheimer’s, suggesting underlying pathologic mechanisms.
Our approach captured the complex morphological alterations of the ChP in AD. These findings provide valuable knowledge that AD pathologies may disrupt ChP structure, contributing to clinical progression. The pathologic substrates underlying these ChP morphological features remain to be elucidated, necessitating further investigation through imaging-histopathological comparison studies.
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Lin et al. (2025) studied this question.
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