November 28, 2025BMC Pharmacology and ToxicologyOpen Access

Biochemical, histopathological, and immunohistochemical study on the ameliorative effect of crocin against lipopolysaccharide‑induced hippocampal toxicity in male albino rats

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Authors

EAEatemad A. Awadalla OMOla Mohamed AAAhmed Abdelsadik

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Implication

Research shows crocin improves memory and reduces neuroinflammation in male rats with lipopolysaccharide-induced toxicity, suggesting its therapeutic potential.

Key Points

Crocin treatment significantly alleviates memory impairments in male albino rats with LPS-induced neuroinflammation.
Key findings include reduced levels of interleukin-1β and tumor necrosis factor-α in treated rats.
Biochemical and histopathological evaluations demonstrate positive changes in hippocampal tissue after crocin administration.
Results highlight crocin's promise as a therapy for neuroinflammation-related conditions.

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Awadalla et al. (2025) studied this question.

synapsesocial.com/papers/6928f106a65b730b9ea79b2c https://doi.org/10.1186/s40360-025-01021-y

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Implication

Research shows crocin improves memory and reduces neuroinflammation in male rats with lipopolysaccharide-induced toxicity, suggesting its therapeutic potential.

Biochemical, histopathological, and immunohistochemical study on the ameliorative effect of crocin against lipopolysaccharide‑induced hippocampal toxicity in male albino rats

Discussion

Member takes

Implication

Key Points

Cite This Study

Biochemical, histopathological, and immunohistochemical study on the ameliorative effect of crocin against lipopolysaccharide‑induced hippocampal toxicity in male albino rats

Discussion

Member takes

Implication

Key Points

Cite This Study

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