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November 28, 2025BMC Oral HealthOpen Access

Association between prophylactic antibiotics and surgical site infections in bimaxillary orthognathic surgery: a retrospective study

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Authors

RURyuta UrakawaYHYuto HorieMOMinako Ohishi

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Overview

Retrospective analysis reveals sulbactam/ampicillin reduces surgical site infections compared to ampicillin, indicating improved antibiotic efficacy.

Key Points

  • Higher surgical site infections observed with ampicillin compared to sulbactam/ampicillin after bimaxillary surgery.
  • SSI incidence in ampicillin group was 46% higher, emphasizing the need for effective prophylactic antibiotics.
  • Retrospective analysis of 115 patients undergoing Le Fort I and bilateral sagittal split osteotomy using four antibiotic regimens.
  • Selecting appropriate antibiotics is crucial for minimizing infection risk following bimaxillary orthognathic surgery.

Cite This Study

Urakawa et al. (2025) studied this question.

synapsesocial.com/papers/6928f113a65b730b9ea79ea5https://doi.org/10.1186/s12903-025-07246-x
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