Breaking the resistance: a narrative review of the evolution from traditional drugs to precision therapies in epilepsy

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Narrative review compares conventional and emerging therapies for drug-resistant epilepsy, highlighting global disparities and access issues.

Emerging therapies promise improved management of drug-resistant epilepsy, addressing the existing treatment gap.
Cannabidiol and responsive neurostimulation demonstrate efficacy but encounter accessibility challenges, especially in low-income areas.
Surgical resection, vagus nerve stimulation, and ketogenic diet remain key components of conventional epilepsy treatment.
This review highlights the need for equitable care and emphasizes the importance of personalized treatment approaches.

Patel et al. (2025) studied this question.

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Narrative review compares conventional and emerging therapies for drug-resistant epilepsy, highlighting global disparities and access issues.