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November 28, 2025BMC GeriatricsOpen Access

Cumulative effect of intrinsic capacity domains on geriatric syndromes and functionality in older inpatients

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Authors

NGNagihan Sözen GencerSCSibel CavdarFKFatma Özge Kayhan Koçak

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Overview

Retrospective study reveals that declines in cognition and vitality strongly predict functional impairments and frailty in hospitalized older adults.

Key Points

  • Cognitive impairment is linked to a nearly six-fold increase in fall risk, emphasizing the need for regular assessment.
  • Logistic regression models identified significant associations between intrinsic capacity domains and geriatric syndromes.
  • Almost 60% of older inpatients exhibited moderate to severe declines in intrinsic capacity, particularly in vitality and locomotion.
  • Routine evaluations of gait speed and psychological well-being may inform targeted interventions for at-risk individuals.

Cite This Study

Gencer et al. (2025) studied this question.

synapsesocial.com/papers/6928f12ea65b730b9ea7a691https://doi.org/10.1186/s12877-025-06697-9
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Cumulative effect of intrinsic capacity domains on geriatric syndromes and functionality in older inpatients2025 · 5 citations
  2. 2Intrinsic capacity and recent falls in adults 80 years and older living in the community: results from the ilSIRENTE Study2024 · 25 citations
  3. 3Intrinsic capacity and mortality in community-dwelling octogenarians: a network analysis from the ilSIRENTE study2026
  4. 4Factors Associated With Good Intrinsic Capacity in Community-Dwelling Older Adults2025
  5. 5Heterogeneity of intrinsic capacity and associations with adverse health outcomes in China: a large community-based cross-sectional study2026