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Multidisciplinary management and molecular characterization of inferior vena cava leiomyosarcoma: a case report

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Local recurrence noted four months post-surgery, suggesting chemotherapy with doxorubicin remains critical after surgical resection.
Next-generation sequencing identified TP53 and TSC2 mutations, which inform tumor characterization and treatment strategies.
A multidisciplinary approach involving various specialties was key for successful management of this rare tumor type.
Postoperative recovery was uncomplicated apart from mild renal impairment, enabling further treatment options.

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Case report highlights tumor surgery and chemotherapy impact on prognosis in inferior vena cava leiomyosarcoma.

Pini et al. (2025) studied this question.

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