November 30, 2025Nature CommunicationsOpen Access

Inferring intrinsic neural timescales using optimal control theory

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Observational analysis finds correlations between model-based and empirical intrinsic neural timescales, suggesting insights into brain connectivity.

Model-based intrinsic neural timescales correlate with empirical measures of cognition.
Analysis across multiple datasets indicates consistent results across different species.
The framework enhances understanding of brain structure and dynamics via network control theory.
Findings support a more realistic model of brain connectivity, with implications for neuroscience and clinical applications.

Kim et al. (2025) studied this question.

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Observational analysis finds correlations between model-based and empirical intrinsic neural timescales, suggesting insights into brain connectivity.