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This is a In Vitro Study study.

November 30, 2025BiochemistryOpen Access

SARS-CoV-2 Spike Protein Amyloid Fibrils Impair Fibrin Formation and Fibrinolysis

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Impaired fibrin formation was linked to Spike Protein in Long COVID patients, affecting blood clot dynamics.
The analysis focuses on the coagulation cascade, revealing critical interactions that inhibit proper fibrin formation.
Spike Protein affects fibrin formation by altering normal coagulation processes, contributing to persistent inflammation.
These findings may highlight new pathways affecting patients with Long COVID, warranting further exploration of treatment options.

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Observational analysis shows impaired fibrin formation in Long COVID, indicating Spike Protein's role in coagulation issues.

Westman et al. (2025) studied this question.

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