November 30, 2025BMC OphthalmologyOpen Access

Severe retinopathy induced by low-dose tamoxifen: a 10-month follow-up analysis based on multimodal imaging

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Low-dose tamoxifen worsens visual impairment linked to retinopathy.
Baseline OCTA vascular markers indicate progressive visual impairment over 10 months of treatment.
Observational analysis leveraging multimodal imaging and looking at traditional dosage thresholds.
Findings support reevaluation of toxicity thresholds in obesity context.

Implication

Analysis shows tamoxifen-induced retinopathy correlates with visual impairment in obese individuals, suggesting new toxicity thresholds.

Abstract

This case challenges traditional TAM-R dosage thresholds, suggesting obesity may exacerbate toxicity. Baseline OCTA vascular markers correlate with irreversible visual impairment, offering novel insights for prognostic evaluation.

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Cite This Study

Zhang et al. (2025) studied this question.

synapsesocial.com/papers/692b944c1d383f2b2a378de7 https://doi.org/10.1186/s12886-025-04499-6

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Implication

Analysis shows tamoxifen-induced retinopathy correlates with visual impairment in obese individuals, suggesting new toxicity thresholds.

Severe retinopathy induced by low-dose tamoxifen: a 10-month follow-up analysis based on multimodal imaging

Key Points

Implication

Abstract

Discussion

Cite This Study

Severe retinopathy induced by low-dose tamoxifen: a 10-month follow-up analysis based on multimodal imaging

Key Points

Implication

Abstract

Discussion

Cite This Study

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