November 30, 2025CellsOpen Access

Psychedelics in Multiple Sclerosis: Mechanisms, Challenges, and Prospects for Neuroimmune Modulation and Repair

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Review evaluates psychedelics effects on neuroinflammation and immune modulation in multiple sclerosis, suggesting new therapeutic avenues.

Psychedelics may improve synaptic plasticity by targeting neuroinflammation in multiple sclerosis.
Evidence indicates psychedelics impact pro-inflammatory cytokines like IL-6, promoting neuroimmune modulation.
Assessment of current pharmacology reveals challenges for clinical applications in autoimmune settings.
Potential role of psychedelics underscores need for detailed studies on non-hallucinogenic compounds in MS treatment.

A 2025 study studied this question.

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Review evaluates psychedelics effects on neuroinflammation and immune modulation in multiple sclerosis, suggesting new therapeutic avenues.