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November 30, 2025Frontiers in ImmunologyOpen Access

Preoperative TACE with PD-1 inhibitors and TKIs in beyond “up-to-seven” hepatocellular carcinoma: a propensity score matched analysis

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Authors

DZDeyuan ZhongYLYuxin LiangYCYa-hui Chen

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Overview

Observational analysis showed improved overall survival in hepatocellular carcinoma patients undergoing neoadjuvant TACE.

Key Points

  • The studying of neoadjuvant TACE treatment resulted in better overall survival compared to surgery alone.
  • The median overall survival was significantly higher in the neoadjuvant group, seen in a duration of 26 months.
  • Analysis involved a retrospective cohort of 126 patients with a matched design to reduce confounders.
  • The findings suggest that neoadjuvant therapy may be advantageous for hepatocellular carcinoma surgeries.

Cite This Study

Zhong et al. (2025) studied this question.

synapsesocial.com/papers/692b9d7b1d383f2b2a3794f2https://doi.org/10.3389/fimmu.2025.1657371
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