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Observational analysis shows high yields in synthesis process with imides and trimethylamine as catalyst.
An efficient 1,6‐conjugate addition for the construction of C–N bonds from the reaction of para ‐Quinone methides ( p ‐QMs) and the weak nucleophilic nitrogen atom of imides was reported. Studies have shown that trimethylamine (Et 3 N) is an essential catalyst for ensuring the successful completion of this synthesis process. The reaction features a wide range of substrates, simple operation, good group tolerance, and high yields.
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