Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
November 30, 2025Health Science ReportsOpen Access

Joint Association of Depression and Sleep Duration With All‐Cause and Cardiovascular Mortality: A Cross‐Sectional Study With Inflammation Mediation Analysis

View Full Paper
Ask AI
Bookmark
Share

Discussion

Loading...

Member takes

Overview

Cross-sectional study reveals depression and short sleep duration heighten mortality risk, indicating potential inflammatory involvement.

Key Points

  • Mortality risk significantly increases with depression and abnormal sleep duration, indicating a crucial mental health link.
  • Participants with depression had a 40% higher risk for all-cause mortality and 79% for cardiovascular mortality compared to non-depressed individuals.
  • Multivariate Cox proportional hazards regression was applied to evaluate the joint effects of depression and sleep duration on mortality risk.
  • The analysis highlights the significance of considering inflammatory factors such as C-reactive protein in assessing health risks.

Cite This Study

A 2025 study studied this question.

synapsesocial.com/papers/692b9da01d383f2b2a37a2e4https://doi.org/10.1002/hsr2.71550
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Joint Association of Depression and Sleep Duration With All‐Cause and Cardiovascular Mortality: A Cross‐Sectional Study With Inflammation Mediation Analysis2025
  2. 2The individual and joint associations of depression and sleep duration with cardiometabolic diseases and mortality: A prospective cohort study2022 · 23 citations
  3. 3All‐Cause and Cardiovascular Mortality in Relation to Sleep Duration: A Community‐Based Cohort With Over 30 Years of Follow‐Up2026
  4. 4Sleep-duration abnormality, depressive symptoms, and cardiometabolic indicators: evidence from NHANES 2013–20232026
  5. 5Association of Sleep Duration With All-Cause and Cardiovascular Mortality: A Prospective Cohort Study2022 · 43 citations