Galectins mediate glucose homeostasis in pregnancy, with chronic associations in obesity and insulin resistance, indicating potential for targeted interventions.
Galectins exhibited distinct patterns of association with glucose homeostasis during the second trimester of pregnancy. Gal-3 and gal-9 are associated with chronic conditions such as pre-pregnancy obesity and insulin resistance, whereas gal-1 appears to be particularly sensitive to the acute glucose challenge.
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García et al. (2025) studied this question.
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