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November 30, 2025Therapeutic Advances in Medical OncologyOpen Access

Treatment response and prediction model of radiotherapy for hepatocellular carcinoma with macrovascular tumor thrombus: a multicenter retrospective study

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Authors

QHQizhen HuangJYJing YangXZXiaohong Zhong

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Overview

Retrospective analysis shows radiotherapy improves treatment response in hepatocellular carcinoma with portal vein tumor thrombus, informing the nomogram model.

Key Points

  • Radiotherapy markedly improved treatment response in hepatocellular carcinoma with macrovascular tumor thrombus, especially portal vein tumor thrombus.
  • The overall objective response rates were 56.32% for portal vein tumor thrombus, indicating significant treatment benefits.
  • Multivariate logistic regression analysis was performed to develop a nomogram that predicts treatment response based on tumor size and thrombus type.
  • This nomogram showed strong predictive performance, supporting its clinical utility for personalized treatment strategies in hepatocellular carcinoma.

Cite This Study

Huang et al. (2025) studied this question.

synapsesocial.com/papers/692b9da91d383f2b2a37a4cdhttps://doi.org/10.1177/17588359251392117
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Efficacy of radiotherapy in combined treatment of hepatocellular carcinoma patients with portal vein tumor thrombus: a real-world study2024 · 3 citations
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  5. 5Integration of multiparametric MRI and clinical indicators to predict response to immune-targeted therapy in patients with advanced hepatocellular carcinoma2026