Synthesis and Characterizations of Alginate/Agarose Hydrogel Incorporated with Hydroxyapatite Extract Fish Bone for Potential Bone Healing Applications

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Enhanced swelling rates observed in alginate-based hydrogels, indicating improved water retention and biocompatibility.
Physicochemical properties characterized by Fourier transform infrared spectroscopy and scanning emission microscope reflect successful hydroxyapatite integration.
The synthesis involved ionic cross-linking using calcium chloride, highlighting an efficient fabrication method for bone replacement materials.
The findings suggest promising applications in tissue engineering, stressing the importance of hydroxyapatite sourced from fish bones.

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Synthesis optimized physicochemical properties of biocomposite hydrogels, indicating potential for bone healing applications.

Song et al. (2025) studied this question.

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