Observational analysis highlights the mediating role of frailty in reducing anxiety and depression in older adults with chronic disease comorbidities.
Frailty serves as a critical mediator between disability, anxiety and depression in older adults with chronic disease comorbidity. Targeted interventions addressing disability and frailty may significantly mitigate anxiety and depression, thereby improving mental health and quality of life in this vulnerable population.
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Yang et al. (2025) studied this question.
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