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December 2, 2025Therapeutic Advances in Medical OncologyOpen Access

Nab-paclitaxel-based chemotherapy with or without anti-PD-(L)1 immunotherapy as a second-line treatment for advanced biliary tract cancer: a real-world retrospective study

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Authors

NZNan ZhouXLXinyi LiMGMingyou Gao

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Overview

Real-world study finds nab-paclitaxel shows promising efficacy in biliary tract cancer patients, highlighting the impact of second-line treatment.

Key Points

  • Overall survival was assessed, showing a median of 15.17 months in the entire patient cohort.
  • Nab-paclitaxel chemotherapy indicated a 21.4% response rate and notable adverse events relevant to treatment effectiveness.
  • The retrospective analysis covered patients treated at West China Hospital over five years, focusing on therapy comparisons.
  • Findings suggest nab-paclitaxel is a promising option for second-line treatment in biliary tract cancer, implying further exploration is warranted.

Cite This Study

Zhou et al. (2025) studied this question.

synapsesocial.com/papers/692e3d796c9b3ab28c18705bhttps://doi.org/10.1177/17588359251389753
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