Plasma exchange as an effective treatment for refractory pure red cell aplasia post-ABO-incompatible hematopoietic stem cell transplantation: a rare complication

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Case report shows treatment success for refractory PRCA in a chronic myeloid leukemia patient, highlighting treatment guidelines need.

Hematologic recovery observed following plasma exchange in anemia post-transplant, improving hemoglobin from 6 to 16 g/dL.
Patient unresponsive to several immunosuppressive agents prior to plasma exchange treatments, demonstrating treatment complexity.
Case report details significant improvement in refractory pure red cell aplasia after ten plasma exchange sessions over five weeks.
Study points to a need for further research to establish comprehensive treatment guidelines for rare PRCA cases.

Khalaf et al. (2025) studied this question.

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