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December 2, 2025Scientific Reports5 citationsOpen Access

Assessing the quality and educational applicability of AI-generated anterior segment images in ophthalmology

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YYYizhou YangLBLifang BaiYRYuecheng Ren

Key Points

  • AI-generated images may enhance training resources in ophthalmology, specifically for cases like entropion.
  • Key evaluation metrics included text accuracy and image reliability rated by 20 ophthalmologists.
  • Juniors rated images higher than seniors, revealing expertise-related differences in perceived educational value.
  • Ethical oversight is essential before integrating AI-generated atlases into formal ophthalmic curricula.

Abstract

Abstract Text-to-image (T2I) artificial intelligence models are being increasingly explored in medical education, yet their utility in ophthalmology remains unclear. Slit-lamp anterior segment photography, as a cornerstone of ophthalmic training, provides an ideal context for evaluation. We assessed 40 cases of anterior segment disease. The text descriptions were generated using GPT-4o, and the corresponding images were synthesized via Sora Turbo. Readability was analysed with the Flesch Reading Ease (FRE), Flesch‒Kincaid Grade Level (FKGL), and Gunning Fog Scale (GFS). Twenty ophthalmologists (10 juniors, 10 seniors) rated image-text pairs across five dimensions—text accuracy, image reliability, recognizability, educational value, and generation stability—using a 5-point Likert scale. Entities with distinct morphological features, such as cataracts and subconjunctival haemorrhages, received the highest total scores, whereas those with entropion and corneal foreign bodies scored the lowest. Readability analysis indicated advanced text complexity. Senior ophthalmologists consistently provided lower ratings than junior clinicians did, highlighting expertise-related differences in perceived educational value. Sora Turbo can generate clinically useful anterior segment images for educational purposes, particularly for pathologies with prominent morphological features. This first systematic evaluation in ophthalmology demonstrates the promise of AI-generated atlases as scalable teaching resources for early-stage trainees while emphasizing the need for expert validation and ethical oversight before integration into formal curricula.

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Cite This Study

Yang et al. (2025) studied this question.

synapsesocial.com/papers/692e3d846c9b3ab28c1873e2https://doi.org/10.1038/s41598-025-27020-x
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Evaluating Text-to-Image Generation in Pediatric Ophthalmology2025
  2. 2The Role of Artificial Intelligence in Teaching Ophthalmology Skills: A Systematic Review2026
  3. 3Entering the era of photorealistic AI-generated medical images2026
  4. 4Using artificial intelligence to improve human performance: efficient retinal disease detection training with synthetic images2024 · 20 citations
  5. 5Ocular Pathology and Genetics: Transformative Role of Artificial Intelligence (AI) in Anterior Segment Diseases2024 · 2 citations