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Analysis reveals dysregulation of biomarkers in early pregnancy, suggesting severe implications for preeclampsia assessment.
Early-pregnancy plasma lncRNAs and mRNAs are markedly dysregulated in PE and correlate with pathogenic pathways. Notably, lncRNAs with |log₂FC| ≥ 5 and mRNAs with |log₂FC| ≥ 6 may serve as novel biomarkers for early PE prediction.
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Zhang et al. (2025) studied this question.
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