Crystal structures, thermal properties and intermolecular interactions of new benzamide-based derivatives

Two benzamide-based derivatives were synthesized and their structures solved for the first time. The successful syntheses of N -ethyl-4-iodobenzamide (C 9 H 10 INO, NE4IBA) and N -ethyl-4-ethynylbenzamide (C 11 H 11 NO, NE4EBA) were achieved via a simple synthetic route. The molecules of NE4IBA in the crystal form one-dimensional double chains with strong hydrogen bonding and weak I...I halogen interactions, while NE4EBA forms two-dimensional hydrogen-bonded layers, including acetylene moieties engaging in C—H...O interactions within a rigid planar layer packing arrangement. Intermolecular N—H...O interactions between the amide groups dominate in both crystal structures. The strong exothermal effect of acetylene-group polymerization was detected immediately after melting NE4EBA using a simultaneous thermal analysis.