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December 4, 2025Advanced Biomedical ResearchOpen Access

Competing Endogenous RNA Networks Reveal Long Non-coding RNAs as Potential Prognostic Biomarkers in Gastric Cancer: A Systematic Review and Meta-Analysis

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Authors

SSSadra Salehi-MazandaraniAVAmirhossein VedaeiPNParvaneh Nikpour

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Overview

Systematic review and meta-analysis report prognostic biomarkers in gastric cancer, highlighting competing endogenous RNA networks and long noncoding RNAs.

Key Points

  • Meta-analysis confirms significant prognostic biomarkers for gastric cancer based on long noncoding RNAs.
  • 56 studies included, evaluating 350 unique lncRNAs and their association with overall survival in gastric cancer.
  • Assessment included sensitivity analysis and evaluation of publication bias among collection databases.
  • Study supports potential of various lncRNAs, suggesting further research on their functions in gastric cancer.

Cite This Study

Salehi-Mazandarani et al. (2025) studied this question.

synapsesocial.com/papers/6930dc6bea1aef094cca1ffdhttps://doi.org/10.4103/abr.abr_185_25
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  1. 1The revised JBI critical appraisal tool for the assessment of risk of bias for cohort studies2024 · 183 citations
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  3. 3Identification and Validation of a Potent Multi-lncRNA Molecular Model for Predicting Gastric Cancer Prognosis2021 · 10 citations