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December 4, 2025Biomedical Chromatography

Comprehensive UHPLC‐ESI‐Orbitrap‐MS Profiling and Bioactivity‐Guided Fractionation of Euphorbia greenwayi : Mechanistic Insights Into Anti‐Inflammatory and Antiaging Bioactive Metabolites

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Authors

AEAhmed F. EssaAEAsmaa S. Abd ElkarimRARania F. Ahmed

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Overview

Comprehensive analysis shows bioactivity and anti-inflammatory effects in Euphorbia greenwayi, highlighting therapeutic potential of phenolic acids and flavonoid glycosides.

Key Points

  • EG5 fraction showed significant anti‐inflammatory effects inhibiting COX‐2, enhancing its therapeutic potential.
  • Analysis identified various bioactive metabolites including tricin and xanthurenic acid linked to antiaging properties.
  • Multivariate data analysis categorized fractions based on their phytochemical profile, revealing important chemical classes.
  • Findings support further pharmacological studies on Euphorbia greenwayi and its bioactive compounds for therapeutic applications.

Cite This Study

Essa et al. (2025) studied this question.

synapsesocial.com/papers/6930dc6bea1aef094cca2076https://doi.org/10.1002/bmc.70268
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