Exploratory analysis shows dileucine with essential amino acids improves anabolism after resistance exercise, suggesting a key role for leucine retention.
Dileucine-supplemented EAA and BCAA support greater whole-body anabolism compared with COL after resistance exercise independent of attenuation in urinary estimates of myofibrillar protein breakdown. Exploratory ex vivo experiments reveal a potential anabolic effect of DIEAA in stimulating MPS. Collectively, these findings suggest that consuming dileucine with sufficient EAA and BCAA increases exogenous leucine retention to support whole-body anabolism during postexercise recovery in individuals performing resistance training.
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Tinline‐Goodfellow et al. (2025) studied this question.
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