What type of study is this?

This is a In Vitro Study study.

December 4, 2025VirusesOpen Access

Evaluation of the Pathogenicity of Highly Virulent Eurasian Genotype II African Swine Fever Virus with MGF505-2R Gene Deletion in Piglets

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Assessment reveals reduced viremia and hyperthermia in piglets infected with ASFV-ΔMGF505-2R, suggesting its safety as a vaccine candidate.

ASFV-ΔMGF505-2R showed reduced pathogenicity compared to control virus, indicating safety.
Piglets infected with ASFV-ΔMGF505-2R experienced low levels of viral loads and transient fever.
Study employed a control group with ASFV CN/GS 2018 for comparisons in immune responses.
Findings support the potential of ASFV-ΔMGF505-2R for live attenuated vaccine development.

Xu et al. (2025) studied this question.

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Assessment reveals reduced viremia and hyperthermia in piglets infected with ASFV-ΔMGF505-2R, suggesting its safety as a vaccine candidate.