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December 4, 2025AntibioticsOpen Access

A Quality Improvement Bundle to Reduce Central Line-Associated Bloodstream Infections in Neonatal Intensive Care Unit: An Observational Study

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Authors

LFLeonardo FioravantiMPMaria Francesca PiazzaCDCarlo Dani

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Overview

Observational study shows decline in central line-associated bloodstream infections in neonatal intensive care unit, indicating effective catheter management strategies.

Key Points

  • CLABSI rate decreased significantly from 10.7 to 3.6/1000 central line days after bundle implementation, showing clear improvement.
  • Utilizing a pre-post observational study, 145 umbilical vein catheters and epicutaneo-caval catheters were analyzed for infection rates.
  • Predictive factors for CLABSI outcomes included gestational age and implementation of the quality improvement bundle.
  • The study emphasizes the need for continued monitoring of catheter-related complications following bundle adoption.

Cite This Study

Fioravanti et al. (2025) studied this question.

synapsesocial.com/papers/6930dc9eea1aef094cca2c30https://doi.org/10.3390/antibiotics14121208
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