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December 4, 2025Saudi Pharmaceutical JournalOpen Access

Relevance of topical application of minoxidil laden nano-lipid for hair growth enhancement

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Authors

AAAli M. AlghazalBABandar AlduhbiabHEHeba S. Elsewedy

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Overview

Observational analysis shows topical application of nanocarrier minoxidil improves hair growth in mice, indicating potential for hair loss treatment.

Key Points

  • The optimized nanocarrier formulation demonstrated a nanosize of 83.1 nm, promoting effective transdermal delivery and hair growth enhancement.
  • In vitro release of minoxidil reached 75.6% over 6 hours, highlighting the efficacy of nanoemulsion for drug delivery.
  • Response Surface Methodology was employed for optimizing nanoemulsion properties like pH (5.9) and viscosity (26.7 cP), ensuring stability.
  • Stability testing indicated the formulation remained effective at room temperature and refrigerate for 12 months, underlining its practical applications.

Cite This Study

Alghazal et al. (2025) studied this question.

synapsesocial.com/papers/6930e8b6ea1aef094cca2e91https://doi.org/10.1007/s44446-025-00051-1
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