December 4, 2025PLOS Global Public HealthOpen Access

Prevalence of rifampicin resistance in pulmonary tuberculosis: A laboratory-based study

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1.8% of Mycobacterium tuberculosis cases were resistant to rifampicin, highlighting a significant public health concern.
Among 2,225 presumptive tuberculosis cases, overall prevalence was 9.1%, with higher rates in young adults and males.
Retrospective analysis of secondary data from the Microbiology Laboratory supported the findings, utilizing GeneXpert techniques for detection.
Enhancing surveillance systems is crucial given the detection rate of rifampicin resistance is low but concerning.

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Laboratory study finds 9.1% prevalence of Mycobacterium tuberculosis, indicating a need for improved detection strategies in Ghana.

Sewornu et al. (2025) studied this question.

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