Purpose: Bronchopulmonary dysplasia (BPD) is a chronic lung disease and a major cause of morbidity in preterm infants, especially in those requiring prolonged invasive mechanical ventilation. This quality improvement (QI) initiative aimed to reduce the duration of invasive ventilation, thereby lowering the incidence of BPD in very-lowbirth-weight infants.Methods: A multidisciplinary QI initiative was conducted at the neonatal intensive care unit of Seoul National University Bundang Hospital from February 2022 to June 2024 and compared with historical controls from January 2019 to December 2021. Infants born at pppp=0.045). According to subgroup analysis of infants born at p=0.01), but BPD incidence was not significantly different (85.5% vs. 92.7%, p=0.27). In the multivariate logistic regression analysis, only the duration of invasive ventilation was significantly associated with BPD (odds ratio OR, 1.09; 95% confidence interval CI, 1.021 to 1.167; p=0.01), but not birth weight (OR, 0.997; 95% CI, 0.995 to 0.999; p=0.001).Conclusion: A structured multidisciplinary intervention effectively reduced the duration of invasive ventilation and BPD. Continued emphasis on comprehensive care bundles may further benefit premature infants.
Mi Jin Kim (Sun,) studied this question.