What type of study is this?

This is a Systematic Review study.

Meta‐analysis of 1 H‐MRS glutamate profiles in adult schizophrenia spectrum disorders and autism spectrum disorder: Study protocol

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Protocol outlines systematic review to analyze glutamatergic metabolites, indicating neurochemical differences in disorders.

Regional differences in glutamate profiles were highlighted across both schizophrenia spectrum disorders and autism spectrum disorder.
The meta-analysis aims to identify specific glutamatergic biomarkers related to neurochemistry in these populations.
Systematic review will employ random-effects meta-analyses with subgroup analyses based on illness stage and medication status.
Findings may inform future translational research related to diverse psychiatric conditions, including biomarker validation.

Takahashi et al. (2025) studied this question.

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