December 4, 2025MicroorganismsOpen Access

The Gut Microbiome in Stevens–Johnson Syndrome and Sjögren’s Disease: Correlations with Dry Eye

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Discussion

Exploratory study shows alterations in gut microbiome in Stevens–Johnson syndrome, indicating links to dry eye severity.

Dry eye severity correlates with gut microbiome changes in Stevens–Johnson syndrome.
Key findings include significant alterations in Clostridia and Faecalibacterium associations.
Next-generation sequencing was used to analyze the gut microbiome profiles of patients and controls.
Findings suggest a relationship between gut microbiome and ocular surface inflammation.

Frizon et al. (2025) studied this question.

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