December 5, 2025Frontiers in ChemistryOpen Access

A novel reversed phase high performance liquid chromatography approach for stability-indicating simultaneous analysis of brimonidine tartrate and timolol maleate

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Authors

AMAktham Mestareehi AMAktham Mestareehi

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Implication

This approach demonstrates robust method validation for quantifying brimonidine tartrate and timolol maleate, suggesting effective quality control in ophthalmic products.

Key Points

The method revealed significant robustness, confirming its reliability for quality control.
Validation metrics show method accuracy between 98.71% and 101.10% for both drugs, emphasizing precise results.
Chromatographic separation utilized a diode array detector with specific conditions, ensuring effective analysis.
Green analytical chemistry principles indicate the method balances efficiency with sustainability, highlighting its moderate ecological impact.

Cite This Study

Mestareehi et al. (2025) studied this question.

synapsesocial.com/papers/693231118e51979591dcdfd3 https://doi.org/10.3389/fchem.2025.1678541

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Implication

This approach demonstrates robust method validation for quantifying brimonidine tartrate and timolol maleate, suggesting effective quality control in ophthalmic products.

A novel reversed phase high performance liquid chromatography approach for stability-indicating simultaneous analysis of brimonidine tartrate and timolol maleate

Discussion

Member takes

Implication

Key Points

Cite This Study

A novel reversed phase high performance liquid chromatography approach for stability-indicating simultaneous analysis of brimonidine tartrate and timolol maleate

Discussion

Member takes

Implication

Key Points

Cite This Study

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