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December 5, 2025Frontiers in ImmunologyOpen Access

Impact of anti-TB drugs on modulations of T-cell-receptor-mediated signaling events in TB pleurisy patients

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Authors

BJBeenu JoshiOakland University

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Overview

Analysis reveals anti-TB drugs enhance IL-2 production in immune cells, suggesting modulation of T-cell signaling pathways in TB pleurisy treatment.

Key Points

  • Treatment reduces bacterial burden, while persistent immune dysregulation affects T-cell activation pathways.
  • Significant IL-2 enhancement post-treatment in immune cells underlines the impact of signaling pathways.
  • This observational analysis explores alterations in signaling pathways related to TCR activation in TB pleurisy patients.
  • Highlighting, further studies are needed to understand implications for relapse and therapeutic strategies.

Cite This Study

Beenu Joshi (2025) studied this question.

synapsesocial.com/papers/693231118e51979591dce033https://doi.org/10.3389/fimmu.2025.1645200
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