Irradiation with carbon ions shows the greatest antitumor effect in Ehrlich adenocarcinoma cells, indicating a promising treatment avenue.
The regularities of tumor induction and growth in mice were studied during a single ex vivo irradiation of Ehrlich adenocarcinoma ascites cells with a beam of protons, helium ions (⁴Не), and carbon ions (¹²С) at doses of 10, 20, and 30 Gy. It was shown that, when tumor cells were exposed to all types of radiation, a dose-dependent increase in the antitumor effect was observed in the latent period of tumor appearance, the frequency of their induction, and tumor growth inhibition. According to all indices, ¹²C had the greatest antitumor effect, ⁴He occupied an intermediate position, and protons caused the least effect.
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Balakin et al. (2025) studied this question.
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