Access to Allyl- gem -difluorides via Allylation and Cope Rearrangement

HaEun Kim; Seungcheol Han; Yunhui Jang; Yu-Jin Jung; Seung Hwan Cho

doi:10.1039/d5sc08340k

January 1, 2025Chemical ScienceOpen Access

Access to Allyl- gem -difluorides via Allylation and Cope Rearrangement

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Key Points

Allylation aids in creating allyl gem-difluorides, enhancing their utility in organic synthesis.
Key findings demonstrate how fluorinated molecules impact molecular electronics and reactivity.
Analysis of molecular structures shows the potential of allyl gem-difluorides in medicinal chemistry and materials chemistry.
Research highlights the need for innovative methods in the synthesis of fluorinated compounds, especially in drug development.

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Implication

Allylation shows reactivity in organic synthesis, indicating its role in developing fluorinated compounds for medicinal chemistry.

Abstract

Fluorinated molecules play crucial roles in medicinal and materials chemistry, as the presence of fluorine profoundly alters molecular electronics and reactivity. Among them, allyl gem -difluorides have attracted growing attention as...

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Kim et al. (2025) studied this question.

synapsesocial.com/papers/693231288e51979591dce656 https://doi.org/10.1039/d5sc08340k

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Access to Allyl- gem -difluorides via Allylation and Cope Rearrangement

Key Points

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Implication

Abstract

Discussion

Cite This Study

Access to Allyl- gem -difluorides via Allylation and Cope Rearrangement

Key Points

Ask about this paper

Implication

Abstract

Discussion

Cite This Study

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