Observational analysis revealed shared genetic architectures in Primary Open-Angle Glaucoma, suggesting targets for neuroprotective drugs.
Our findings suggest a genetic overlap between POAG and the volumes of visual pathway regions, including shared candidate causal genes. Further investigations are required to elucidate the specific role of the shared genes in the etiology of POAG and to assess their potential as neuroprotective drug targets.
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Aman et al. (2025) studied this question.
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