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December 6, 2025Journal of Drugs in Dermatology

Clindamycin Phosphate 1.2%/Adapalene 0.15%/ Benzoyl Peroxide 3.1% Gel for Moderate-to-Severe Acne: A Pooled Analysis by Age

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Authors

LKLeon KircikLELawrence F. EichenfieldEGEmmy Graber

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Overview

Pooled analysis shows fixed-dose gel improves acne severity in all ages, indicating a viable treatment option for diverse populations.

Key Points

  • Approximately 50% of participants achieved clear or almost clear skin, highlighting the gel's effectiveness.
  • More than 70% reductions in lesion counts were observed, showcasing substantial improvement across the participant group.
  • Fixed-dose, triple-combination gel assessed in varied age groups demonstrates broad applicability and tolerability.
  • Efficacy and tolerance confirm that this treatment may be suitable for managing moderate-to-severe acne effectively across demographics.

Cite This Study

Kircik et al. (2025) studied this question.

synapsesocial.com/papers/69337ce8b3f947a0a125a10fhttps://doi.org/10.36849/jdd.9407
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