Advances and challenges of ZIF-based nanocomposites in immunotherapy and anti-inflammatory therapy

Junlin Qian; Biao Zheng; Ying Pan

doi:10.1039/d5tb02219c

December 2, 2025Journal of Materials Chemistry B

Advances and challenges of ZIF-based nanocomposites in immunotherapy and anti-inflammatory therapy

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Key Points

Immunotherapy shows promise for enhancing treatment outcomes using ZIF-based nanocomposites.
Recent advancements include better drug-loading capacity and pH responsiveness in nanocomposites.
Assessment includes ZIFs' roles in various therapeutic applications for their biocompatibility.
The findings highlight potential challenges in the clinical application of ZIFs in therapy.

Implication

This review highlights advances in immunotherapy using ZIF-based nanocomposites, suggesting improved biocompatibility and drug delivery.

Abstract

Zeolitic Imidazole Frameworks (ZIFs) have garnered significant attention in immunotherapy and anti-inflammatory therapy due to their tunable porosity, high drug-loading capacity, pH responsiveness, and biocompatibility. This review systematically summarizes recent...

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Cite This Study

Qian et al. (2025) studied this question.

synapsesocial.com/papers/69337cefb3f947a0a125a401 https://doi.org/10.1039/d5tb02219c

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Advances and challenges of ZIF-based nanocomposites in immunotherapy and anti-inflammatory therapy

Key Points

Implication

Abstract

Discussion

Cite This Study

Advances and challenges of ZIF-based nanocomposites in immunotherapy and anti-inflammatory therapy

Key Points

Implication

Abstract

Discussion

Cite This Study

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