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Synthesize current evidence regarding zeolites and zeolite imidazolate frameworks (ZIFs) incorporated into hybrid biomaterials for therapeutic, regenerative, and drug delivery applications.

July 1, 2023Materials TodayOpen Access

Zeolites and zeolite imidazolate frameworks on a quest to obtain the ideal biomaterial for biomedical applications: A review

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Synthesize current evidence regarding zeolites and zeolite imidazolate frameworks (ZIFs) incorporated into hybrid biomaterials for therapeutic, regenerative, and drug delivery applications.
Reviewed recent literature on organic-inorganic biomaterials with an emphasis on polymer/zeolite and polymer/ZIF composites.
Assessed biomedical applications spanning drug carriers, wound dressings, tissue engineering scaffolds, and osteoporosis therapies.
Evaluated mechanistic properties underlying antimicrobial efficacy, anticancer responses, material stability, and physiological toxicity.
Polymer/zeolite and polymer/ZIF hybrid matrices provide functional structural support for tissue scaffolds and controlled drug release.
Zeolite-based systems exhibit direct antimicrobial and anticancer mechanisms, serving as promising alternatives to conventional therapeutic carriers.
Translational deployment remains limited by key physicochemical hurdles, specifically material stability, responsiveness to biological stimuli, and potential cytotoxicity.

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Implication

Review reveals versatile therapeutic utility of zeolite composites across biomedical models, suggesting strong potential for advanced drug delivery.

Cite This Study

Matusiak et al. (2023) studied this question.

synapsesocial.com/papers/6a882ab42d13770579f4dcf8 https://doi.org/10.1016/j.mattod.2023.06.008

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Implication

Review reveals versatile therapeutic utility of zeolite composites across biomedical models, suggesting strong potential for advanced drug delivery.

Zeolites and zeolite imidazolate frameworks on a quest to obtain the ideal biomaterial for biomedical applications: A review

Key Points

Discussion

Implication

Cite This Study

Zeolites and zeolite imidazolate frameworks on a quest to obtain the ideal biomaterial for biomedical applications: A review

Key Points

Discussion

Implication

Cite This Study

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