Electrochemical approach enables heterocycle formation from alkenes, suggesting a novel bromination strategy.
A versatile electrochemical method for the intramolecular aminobromination of alkenes has been developed. The method provides access to five‐, six‐, and seven‐membered heterocycles by exploiting tetrabutylammonium bromide as an electrolyte and bromine source. The mild electrochemical generation of Br 2 plausibly allows the formation of a cyclic bromonium intermediate, as supported by density functional theory calculations.
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Colombo et al. (2025) studied this question.
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